Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Otx2  orthodenticle homeobox 2   (Synonyms: E130306E05Rik)
Results	Reference
1*	J:89361 Acampora D, Annino A, Puelles E, Alfano I, Tuorto F, Simeone A, OTX1 compensates for OTX2 requirement in regionalisation of anterior neuroectoderm. Gene Expr Patterns. 2003 Aug;3(4):497-501
1*	J:49817 Acampora D, Avantaggiato V, Tuorto F, Briata P, Corte G, Simeone A, Visceral endoderm-restricted translation of otx1 mediates recovery of otx2 requirements for specification of anterior neural plate and normal gastrulation. Development. 1998 Dec;125(24):5091-104
1*	J:72726 Acampora D, Boyl PP, Signore M, Martinez-Barbera JP, Ilengo C, Puelles E, Annino A, Reichert H, Corte G, Simeone A, OTD/OTX2 functional equivalence depends on 5' and 3' UTR-mediated control of Otx2 mRNA for nucleo-cytoplasmic export and epiblast-restricted translation. Development. 2001 Dec;128(23):4801-13
1*	J:153562 Acampora D, Di Giovannantonio LG, Di Salvio M, Mancuso P, Simeone A, Selective inactivation of Otx2 mRNA isoforms reveals isoform-specific requirement for visceral endoderm anteriorization and head morphogenesis and highlights cell diversity in the visceral endoderm. Mech Dev. 2009 Oct;126(10):882-97
1*	J:29276 Acampora D, Mazan S, Lallemand Y, Avantaggiato V, Maury M, Simeone A, Brulet P, Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation. Development. 1995 Oct;121(10):3279-90
1	J:53300 Acampora D, Simeone A, The TINS Lecture. Understanding the roles of Otx1 and Otx2 in the control of brain morphogenesis. Trends Neurosci. 1999 Mar;22(3):116-22
1	J:81247 Beck S, Le Good JA, Guzman M, Ben Haim N, Roy K, Beermann F, Constam DB, Extraembryonic proteases regulate Nodal signalling during gastrulation. Nat Cell Biol. 2002 Dec;4(12):981-5
1*	J:71034 Boyl PP, Signore M, Acampora D, Martinez-Barbera JP, Ilengo C, Annino A, Corte G, Simeone A, Forebrain and midbrain development requires epiblast-restricted Otx2 translational control mediated by its 3' UTR. Development. 2001 Aug;128(15):2989-3000
1	J:70006 Brennan J, Lu CC, Norris DP, Rodriguez TA, Beddington RS, Robertson EJ, Nodal signalling in the epiblast patterns the early mouse embryo. Nature. 2001 Jun 21;411(6840):965-9
1*	J:29881 Haegel H, Larue L, Ohsugi M, Fedorov L, Herrenknecht K, Kemler R, Lack of beta-catenin affects mouse development at gastrulation. Development. 1995 Nov;121(11):3529-37
1*	J:64866 Kimura C, Yoshinaga K, Tian E, Suzuki M, Aizawa S, Matsuo I, Visceral endoderm mediates forebrain development by suppressing posteriorizing signals. Dev Biol. 2000 Sep 15;225(2):304-21
1	J:120359 Kimura-Yoshida C, Tian E, Nakano H, Amazaki S, Shimokawa K, Rossant J, Aizawa S, Matsuo I, Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5919-24
1*	J:86839 Liguori GL, Echevarria D, Improta R, Signore M, Adamson E, Martinez S, Persico MG, Anterior neural plate regionalization in cripto null mutant mouse embryos in the absence of node and primitive streak. Dev Biol. 2003 Dec 15;264(2):537-49
1	J:51304 Morrisey EE, Tang Z, Sigrist K, Lu MM, Jiang F, Ip HS, Parmacek MS, GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo. Genes Dev. 1998 Nov 15;12(22):3579-90
1*	J:67152 Perea-Gomez A, Lawson KA, Rhinn M, Zakin L, Brulet P, Mazan S, Ang SL, Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo. Development. 2001 Mar;128(5):753-65
1	J:51542 Tomihara-Newberger C, Haub O, Lee HG, Soares V, Manova K, Lacy E, The amn gene product is required in extraembryonic tissues for the generation of middle primitive streak derivatives. Dev Biol. 1998 Dec 1;204(1):34-54
1	J:60110 Tsang TE, Kinder SJ, Tam PP, Experimental analysis of the emergence of left-right asymmetry of the body axis in early postimplantation mouse embryos. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):493-503
1*	J:202158 Wang X, Marcinkiewicz M, Gatain Y, Bouchard M, Mao J, Tremblay M, Uetani N, Hanissian S, Qi S, Wu J, Luo H, Investigation of tissue-specific expression and functions of MLF1-IP during development and in the immune system. PLoS One. 2013;8(5):e63783